Collaborative Care in Myelofibrosis: Polling Question 2 Answer Rationale

Which prognostic scoring system includes platelet count as a prognostic variable? 

a. DIPSS

b. DIPSS+

c. GIPSS

d. MIPSS-70+ 2.0

Rationale

The Dynamic International Prognostic Scoring System-Plus (DIPSS+) is the only listed prognostic scoring system that includes platelet count as a prognostic factor (platelet count is also a prognostic factor in the Mutation-enhanced International Prognostic Scoring System [MIPSS-70]). Neither the DIPSS, Karyotype-enhanced MIPSS-70 (MIPSS-70+ 2.0), nor the Genetically Inspired Prognostic Scoring System (GIPSS) includes platelet count as a prognostic factor.

References

  1. National Comprehensive Cancer Network (NCCN). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®): Myeloproliferative Neoplasms (v2.2023). Updated August 29, 2023. Accessed August 29, 2023. https://www.nccn.org/professionals/physician_gls/pdf/mpn.pdf