Clinical Treatment Scenarios: Vitiligo Pathogenesis and the Role of JAK Inhibition – Clinical Brief #1

Therapy in Newly Diagnosed Patients


“If you’ve seen one patient with vitiligo…you’ve seen one patient with vitiligo,” Dr. David Rosmarin is fond of saying. This relatively common dermatologic disorder can present in a wide variety of ways and its impact on patients’ quality of life can be profound yet highly individual.

There is an unmet clinical need for therapies for vitiligo repigmentation. Traditionally, therapies have been ineffective for ~50% of patients, with highly variable treatment responses, and none have been approved specifically for repigmentation until recently, with the approval of ruxolitinib cream.

Next, listen to what expert Dr. David Rosmarin has to say about how quality of life is assessed in younger patients, what the best approach is to elicit the patient’s treatment goals, and what treatment options should be considered for nonsegmental vitiligo.