Biomarkers and Biologics: Advancing Selection and Monitoring of Targeted Therapies for Severe Asthma – Clinical Brief #1

Defining Severe Asthma and Recommendations for Use of Biologics

Please watch the video below, then read the supporting information that follows and advance to the posttest by clicking the Continue to posttest button.

 

 

Definitions of uncontrolled, difficult-to-treat, and severe asthma from the GINA 2022 Main Report are listed in the graphic below.

When managing patients with severe asthma, healthcare providers should first confirm T2 inflammation, then assess phenotype, address contributing factors, comorbidities, and exacerbations, and then consider add-on biologic for patients with T2 inflammation, exacerbations, and poor symptom control despite high-dose ICS-LABA.