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Burden of AD

Psychosocial and Health-related Burden of AD

Detrimental to QOL

  • Heavy psychosocial impact
  • Due to stigma, embarrassment, isolation, unpredictability of flares
  • Anxiety and depression
  • Suicidal ideation reported by ~20% with severe disease
  • Negative impact on academic and job-related performance
  • Relationship to autism in children
  • Attention-deficit/hyperactivity disorder important comorbidity in children

Negative effect on sleep (mostly due to pruritus)

  • Can lead to excessive daytime sleepiness and fatigue
  • Can exacerbate anxiety, depression, and reduced HRQOL

Increased risk of cutaneous and systemic infections

Heavy care and financial burden for parents, caregivers

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Economic Burden of AD

HRQOL, health-related quality of life; QOL, quality of life.