PROVIDER STATEMENT

Provided by Integrity Continuing Education, Inc.

SUPPORTER ACKNOWLEDGEMENT

Supported by independent educational grants from Biogen and EMD Serono, Inc.

TWEETORIAL FOCUS

Approach to the Treatment of Multiple Sclerosis (MS)

PROGRAM OVERVIEW

Although the multifactorial causes of multiple sclerosis (MS) are not known, an improved understanding of the neuroimmunologic pathogenesis has led to the development of a wide variety of disease-modifying treatments (DMTs). While there is no cure for MS, these treatments can reduce disease activity and delay MS progression and disability. However, having more DMT options than ever, and more still in clinical development, further complicates treating an already complex condition. With a wide variety of mechanisms of action (MOAs), selecting the optimal DMT is a formidable challenge with the opportunity to improve short- and long-term outcomes. Yet, using a treatment that is unsuitable to the patient’s individual disease activity, prognosis, and preferences is likely to lead to intolerable adverse events (AEs) and nonadherence. Given an MS patient’s immunosuppressed status and increased risk of infection, adherence issues are further compounded during the pandemic as a result of stay-at-home orders. Personalized treatment incorporates patient preferences for selecting, starting, switching, and stopping therapies as the patient’s circumstances change, as the disease progresses, and as the patient ages. Parsing the therapeutic alternatives can yield the most benefit when an interdisciplinary shared decision-making (SDM) approach is used. MS is a therapeutic area that is rapidly evolving and neurology clinicians need to remain updated on emerging therapies. Through this initiative, participants will gain the knowledge and competence to develop early, aggressive plans that balance the benefits and risks of MS treatment options in order to optimize patient management through SDM. This is a Twitter-based tutorial designed to provide key information in an accessible format and location.

FACULTY

Aaron Boster, MD Founder and President The Boster Center for Multiple Sclerosis Columbus, Ohio

Barry A. Singer, MD Director, The MS Center for Innovations in Care St. Louis, Missouri

Release date: May 26, 2021 Expiration date: May 26, 2022 Estimated time to complete activity: 0.25 hour(s)

TARGET AUDIENCE

This program is intended for MS specialists, neurologists, internists, nurse practitioners, and physician assistants who are involved in the care of patients with MS.

LEARNING OBJECTIVES

Upon completion of this educational activity, participants should be able to:

Personalize treatment selection when starting, switching, or stopping a pharmacologic based on efficacy, safety, and patient preference
Evaluate the latest data on the efficacy, safety, and dosing/administration of currently approved DMTs to develop optimal individualized treatment strategies for patients with MS

DIRECTIONS TO LEARNER

There are no fees for participating and receiving CME credit for this activity. During the period of May 26, 2021 through May 26, 2022, participants must:

Read the learning objectives and faculty disclosures
Complete the pretest
Study the educational activity
Complete the posttest and the evaluation form

A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 70% or better.

MEDIA

Internet

ACCREDITATION

Physician Continuing Education Accreditation Statement

Integrity Continuing Education, Inc. is accredited with commendation by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION

Integrity Continuing Education, Inc. designates this other activity for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CONTACT INFORMATION

For information about ACCME accreditation of this activity, please contact Integrity Continuing Education, Inc. at (855) 835-4004 or cme@integrityce.com.

DISCLOSURE OF CONFLICTS OF INTEREST

Integrity Continuing Education, Inc. requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Integrity Continuing Education, Inc. for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. All relevant financial relationships have been mitigated. The following faculty/planners reported the financial relationships or relationships to products or devices they or have with ineligible companies related to the content of these CME activities: Aaron Boster, MD Consulting Fees: EMD Serono, Genentech, Genzyme, Novartis Speakers’ Bureaus: EMD Serono, Genentech, Genzyme Barry A. Singer, MD Consulting and/or Speaking Fees: AbbVie, Alexion, Bayer, Biogen, Bristol Myers Squibb (Celgene), EMD Serono, Janssen, Genentech, Greenwich Biosciences, Novartis, Roche, Sanofi Genzyme, Teva, TG Therapeutics Institution Research Grants: AbbVie, Alkermes, Bayer, Biogen, MedImmune, Novartis, Roche, Sanofi Genzyme The Integrity Continuing Education, Inc. planners/managers have nothing to disclose.

DISCLOSURE OF UNLABELED USE

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity Continuing Education, Inc. does not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

PRIVACY POLICY

When you participate in an online educational activity sponsored by Integrity Continuing Education, Inc., you will be asked for your name, degree(s), affiliation(s), street address, telephone number, fax number, and…(continued)

MINIMUM SYSTEM REQUIREMENTS

Minimum Processor: Intel Pentium 4, 2.33 + GHz (or equivalent) Operating Systems: Windows XP, Windows 2000, Windows Vista, Windows 7, Windows 10, and Mac OS Plug-in: Adobe^® Flash^® Player 10

Adobe^® Flash^® Player 10 plug-in should be downloaded
Click on the “Agree and install now” button after unchecking the optional McAfee Security Scan Plus

For optimal performance, the use of Internet Explorer below 8 is not recommended. For a full listing of recommended operating systems, browsers, and system configurations, please click on the link below Click here for more information on minimum system requirements.

DISCLAIMER

The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition.

2021 Multiple Sclerosis Updates: A Focus on New and Emerging Therapies, Best Practices in Clinical Management and Key Considerations During the COVID-19 Era– Tweetorial #2