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Kelly is a 25-year-old woman with asthma (initially diagnosed at the age of 10) who presents with uncontrolled symptoms (ACT=17). She has a history of recurrent exacerbations, including 5 in the past 18 months. Initial evaluation reveals a normal serum IgE and a blood eosinophil count of 350 cells/μl. What is the phenotypic characteristic most closely associated with Kelly?
Her current therapeutic regimen includes a high-dose ICS+LABA, which she has been taking for the past year, and a trial of tiotropium, which she started 60 days prior. Which of the following therapies is the most appropriate option for Kelly?
Robert is a 40-year-old man with uncontrolled asthma symptoms whose current treatment includes high-dose ICS and an LTRA that he has been taking for the past year and a half. Robert’s serum IgE test was positive and his blood eosinophil count was 250 cells/μl. Which of the following therapies is the best option for Robert?
Which of the following is the relative therapeutic target for benralizumab, mepolizumab, and reslizumab?
Which of the following is the relative therapeutic target for dupilumab?
According to recent survey data, approximately what percentage of patients with severe asthma report having discussed development of a personal asthma action plan with their healthcare providers?