On-demand CME/CE webcast previously recorded from the September 25, 2021, Hospital Medicine Summit
Pulmonary arterial hypertension (PAH), a rare yet potentially fatal progressive disease associated with increased pulmonary vascular resistance and pulmonary artery pressure, exerts a considerable burden on quality of life. During the early stages of the disease, patients often present with nonspecific symptoms and subtle physical signs, which can result in late detection and diagnosis. Transthoracic echocardiography is a noninvasive approach used for screening patients with symptoms or risk factors for pulmonary hypertension, including connective tissue disease, and may also provide clinicians with information on disease etiology and prognosis, information which can be used to tailor treatment approaches to ensure better outcomes. In conjunction with early detection and evaluation of treatment response, echocardiography may also predict prognosis in patients with PAH. Today, there are several approved medications that target 3 distinct pathological pathways in PAH, including the prostacyclin, endothelin, and nitric oxide pathways. Currently, there is a growing trend to combine agents from these different therapeutic classes to target multiple pathologic pathways, as this may improve efficacy and optimize clinical outcomes.
Given the diverse, complex, and nonspecific presentation of PAH, a multidisciplinary approach is needed to ensure optimal diagnostic assessment and adherence to combination therapy. This program will provide clinicians with an understanding of echocardiography assessment, increase awareness of recent data from trials on combination therapy, and improve understanding of a patient-centered and multidisciplinary approach to PAH care.
John Ryan, MD, MB, BCh
Director, Pulmonary Hypertension Comprehensive Care Center
Medical Director, Cardiovascular Medical Unit
University of Utah Hospital
Faculty Director of Cardiology Education
University of Utah School of Medicine
Salt Lake City, Utah
This educational activity has been designed to meet the needs of physicians, physician assistants, nurse practitioners, registered nurses, and pharmacists who practice in hospital, internal medicine, and chronic-care settings.
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John Ryan, MD, MB, BCh
Consulting Fees: Bayer, Janssen PH, United Therapeutics
Fees for Non-CME/CE Services: Bayer, Janssen PH, United Therapeutics
The following project managers/planners: Lindsay Borvansky, Ashley Cann, Donna Fausak, Andrea Funk, Liddy Knight, Kim Rodriguez, Rhys Williams, RN, MSN, FNP, Maria Rovere, MTSC, and Patima Tanapat, PhD, reported that they or their spouses/life partners, have no financial relationships or relationships to products or devices with commercial interests related to the content of this CE activity.
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This activity is supported by an educational grant from Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company of Johnson & Johnson.