This activity is provided by Integrity Continuing Education, Inc.
This activity is supported by an educational grant from Apellis Pharmaceuticals, Inc.
If you’ve never heard of paroxysmal nocturnal hemoglobinuria (PNH), you’re not alone. It’s a rare disease that results in the destruction of red blood cells, resulting in severe anemia and high risk for lethal thrombotic events. Started by a mutation in a single gene, PNH is activated through the complement cascade, a less-understood part of the innate immune system. Until recently, the pathogenesis of PNH was poorly understood and there were no effective treatments. Patients had to rely on frequent transfusions of red blood cells and 50% died within 10 years of diagnosis, but the last few years have transformed this orphan disease state into a hotbed of therapeutic activity. A new treatment targeting a different level of the complement cascade was approved in 2021 and numerous other therapies are now in late-phase development.
Join PNH expert Dr. Ilene Weitz as she takes a deep dive into very recently published insights into the pathogenesis, treatment options, and management of this poorly understood hematologic disorder.
Ilene Ceil Weitz, MD
Professor of Clinical Medicine
Keck School of Medicine
University of Southern California
Los Angeles, California
This educational activity is designed for hematologists, oncologists, and other healthcare providers involved in managing care for patients with PNH, including primary care physicians, physician assistants, and nurse practitioners.
Upon completion of this educational activity, participants should be able to:
There are no fees for participating and receiving CME credit for this activity. During the period of June 15, 2023 through June 15, 2024 participants must:
A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 60% or better.
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The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity:
Ilene Ceil Weitz, MD
Consultant: Alexion Pharmaceuticals, Apellis-Sobi Pharmaceuticals, Novartis, Sanofi Pharmaceuticals
Speakers’ Bureau: Alexion Pharmaceuticals
The Integrity Continuing Education, Inc. planners and managers do not have any financial relationships or relationships to products or devices with ineligible companies.
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