Optimizing Treatment Selection in HR+, HER2- Metastatic Breast Cancer

Course Information
Release date: August 23, 2024
Expiration date: November 23, 2024
Estimated time to complete activity: 30 minutes
PROVIDER STATEMENT

Provided by Integrity CE, LLC.

DISCLOSURE OF COMMERCIAL SUPPORT

Supported by educational grants from AstraZeneca, Lilly, Novartis, and Seagen, Inc.

PROGRAM OVERVIEW

This case will focus on a 68-year-old postmenopausal woman who presents with new palpable axillary lymphadenopathy and severe back pain. After workup and testing, she receives a diagnosis of HR+, HER2- metastatic breast cancer.

The discussion will cover the selection of the optimal treatment from the available cyclin-dependent kinase 4 and 6 (CDK 4/6i) combinations. Trials included are MONARCH-3, PALOMA-2, and MONALEESA-2.

Learning Objectives
TARGET AUDIENCE

This educational activity has been designed to meet the needs of medical, surgical, and radiation oncologists, physician assistants, nurse practitioners, nurses, and other healthcare providers involved in treatment and management of patients with breast cancer.

LEARNING OBJECTIVES

Upon completion of this educational activity, participants should be able to:

  • Individualize therapeutic regimens based on the molecular profile of tumors and patient characteristics
  • Implement supportive care strategies to mitigate and manage unique toxicities associated with recently approved and emerging targeted therapies
Faculty Information and Disclosures
FACULTY
Yara Abdou, MD
Assistant Professor
Breast Medical Oncologist
University of North Carolina at Chapel Hill
Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina
Prarthna Bhardwaj, MD, FACP
Fellow
University of Massachusetts
Chan Medical School – Baystate
Springfield, Massachusetts
DISCLOSURE OF CONFLICTS OF INTEREST

Integrity CE, LLC requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any financial relationships with ineligible companies. All identified relevant financial relationships are thoroughly vetted by Integrity CE, LLC for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. All relevant financial relationships have been mitigated.

The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of these CME activities:

Yara Abdou, MD
Advisor: AstraZeneca
Consultant: Exact Sciences

Prarthna Bhardwaj, MD, FACP does not have any financial relationships or relationships to products or devices with ineligible companies.

The Integrity CE, LLC planners and managers do not have any financial relationships or relationships to products or devices with ineligible companies.

Accreditation Information
DIRECTIONS TO LEARNER

There are no fees for participating and receiving CME credit for this activity. During the period of August 23, 2024 through November 23, 2024, participants must:

  • Read the learning objectives
  • Complete the pretest
  • Study the educational activity
  • Complete the posttest and the evaluation form

A statement of credit will be issued only upon receipt of a completed posttest with a score of 50% or better and a completed activity evaluation form.

ACCREDITATION STATEMENT

Integrity CE, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION

Integrity CE, LLC designates this enduring material for a maximum of 0.5 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

CONTACT INFORMATION

For information about ACCME accreditation of this activity, please contact Integrity CE, LLC at (855) 835-4004 or cme@integrityce.com.

DISCLOSURE OF UNLABELED USE

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity CE, LLC does not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimers and Technical Requirements
MEDIA

Internet

PRIVACY POLICY

When you participate in an online educational activity sponsored by Integrity CE, LLC, you will be asked for your name, degree(s), affiliation(s), street address, telephone number and…(continued)

MINIMUM SYSTEM REQUIREMENTS

Minimum Processor: Intel Pentium 4, 2.33 + GHz (or equivalent)
Operating Systems: Windows XP, Windows 2000, Windows Vista, Windows 7, Windows 10, and Mac OS
Plug-in: Adobe® Flash® Player 10

  • Adobe® Flash® Player 10 plug-in should be downloaded
  • Click on the “Agree and install now” button after unchecking the optional McAfee Security Scan Plus

For optimal performance, the use of Internet Explorer below 8 is not recommended

For a full listing of recommended operating systems, browsers, and system configurations, please click on the link below:
Click here for more information on minimum system requirements

DISCLAIMER

The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

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