This activity is provided by Integrity Continuing Education, Inc.
This activity is supported by an educational grant from Alexion Pharmaceuticals, Inc.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare immunologic disorder that leads to the destruction of red blood cells through the complement cascade. Three complement inhibitors (CIs) are now available to treat this disorder that typically affects young adults during their most productive years and results in a high early mortality rate if not treated appropriately. With CIs, patients with PNH can now expect to live a relatively normal lifespan, but only if physicians and other members of the primary care team know how to recognize the signs and symptoms of this disease so patients can be referred to hematologist experts in PNH.
Join expert Dr. Carlos de Castro III to find out what primary care health professionals need to know about when PNH should be suspected, how it is diagnosed and treated, and how to evaluate and monitor treatment response. This video-based activity includes an informative slide presentation and two in-depth clinical case studies.
Carlos M. de Castro III, MD
Professor of Medicine
Department of Medicine
Durham, North Carolina
This educational activity has been designed to meet the needs of physicians in internal medicine, primary care, and family medicine, as well as physician assistants, nurse practitioners, and other healthcare providers who may be involved in managing care for patients with PNH.
Upon completion of this educational activity, participants should be able to:
There are no fees for participating and receiving CME credit for this activity. During the period of January 31, 2023 through January 31, 2024 participants must:
A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 60% or better.
Integrity Continuing Education, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Integrity Continuing Education, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
For information about ACCME accreditation of this activity, please contact Integrity Continuing Education, Inc. at (855) 835-4004 or firstname.lastname@example.org.
Integrity Continuing Education, Inc. requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any financial relationships with ineligible companies. All identified relevant financial relationships are thoroughly vetted by Integrity Continuing Education, Inc. for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations. All relevant financial relationships have been mitigated.
The following faculty/planners reported the financial relationships or relationships to products or devices they have with ineligible companies related to the content of this CME activity:
Carlos M. de Castro III, MD
Consultant: Alexion, Apellis, Biocryst
Data Safety Monitoring Board: Regeneron
Steering Committee: Novartis
The Integrity Continuing Education, Inc. planners and managers have nothing to disclose.
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Integrity Continuing Education, Inc. does not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
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The information provided at this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.