TITLE OF ACTIVITY:

2025 Johns Hopkins Updates in Gastrointestinal Cancers

PRESENTED BY:

Johns Hopkins University School of Medicine and Integrity CE, LLC.

DESCRIPTION

The 2025 Johns Hopkins Updates in Gastrointestinal (GI) Cancers, was a two-day educational event focused on the latest information and updates in gastrointestinal cancers. The conference featured a variety of case-based discussions, including but not limited to hepatobiliary and lower/upper GI cancers, as well as a special keynote session. This activity is designed to meet the needs of all healthcare providers involved in the care and management of patients with GI cancers.

WHO SHOULD PARTICIPATE

This activity is intended for medical, surgical, and radiation oncologists, physician assistants, nurse practitioners, nurses, and other specialists who treat and manage patients with gastrointestinal cancers.

OBJECTIVES

After participating in this activity, the learner will demonstrate the ability to:

Discuss the most current and evidence-based treatment strategies for gastrointestinal cancers, incorporating the latest approvals, updated guidelines, and clinical data.
Implement biomarker-driven approaches to optimize personalized care through targeted treatments for patients with gastrointestinal cancers.
Assess the efficacy and safety of emerging therapies in late-stage clinical development to facilitate their integration into clinical practice.

ACCREDITATION STATEMENT

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT

Johns Hopkins University School of Medicine Office of Continuing Medical Education designates this enduring activity for a maximum amount of 11.0 AMA PRA Category 1 Credits^TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

POLICY ON PRESENTER AND PROVIDER DISCLOSURE

It is the policy of the Johns Hopkins School of Medicine that the presenter and provider globally disclose conflicts of interest. The Johns Hopkins School of Medicine OCME has established policies in place to identify and mitigate relevant conflicts of interest prior to this educational activity. Detailed disclosure will be made prior to presentation of the education.

NOTICE ABOUT OFF-LABEL USE PRESENTATIONS

The Johns Hopkins School of Medicine/Johns Hopkins Updates in GI Cancers Conference may include presentations on drugs or devices, or use of drugs or devices, that have not been approved by the Food and Drug Administration (FDA) or have been approved by the FDA for specific uses only. The FDA has stated that it is the responsibility of the physician to determine the FDA clearance status of each drug or device he or she wishes to use in clinical practice. The Johns Hopkins School of Medicine is committed to the free exchange of medical education. Inclusion of any presentation in this program, including presentations on off-label uses, does not imply an endorsement by Johns Hopkins of the uses, products, or techniques presented.

JOHNS HOPKINS STATEMENT OF RESPONSIBILITY

The Johns Hopkins School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

COPYRIGHT

All rights reserved - The Johns Hopkins School of Medicine. No part of this program may be used or reproduced in any manner whatsoever without written permission except in the case of brief quotations embodied in articles or reviews.

COURSE FORMAT – METHOD OF PARTICIPATION

This enduring material is expected to take approximately 11.0 hours to complete. Once the activity is completed, you must pass the posttest and complete the evaluation with attestation to receive CME credit.

HOW TO OBTAIN CME CREDIT

There are no fees for participating and receiving CME credit for this activity. To receive credit, participants must:

View the content
Complete the posttest and evaluation

The content is available at: https://www.vumedi.com/channel/integrity-ce/tab/2025-johns-hopkins-updates-in-gastrointestinal-gi-cancers/

PREREQUISITES FOR PARTICIPANTS

There are no prerequisites to participate in this activity.

HARDWARE/SOFTWARE REQUIREMENTS

Internet connection.

POST-TEST

A post-test will be conducted at the conclusion of the activity. A grade of at least 70% within three attempts is needed to receive CME credit.

RELEASE DATE

April 30, 2025

EXPIRATION DATE

April 30, 2026

WHAT YOU SHOULD KNOW ABOUT GIFTS TO PHYSICIANS FROM INDUSTRY

Gift giving from the pharmaceutical, device and medical equipment industries to physicians has long been a customary practice. But when gift giving is not practiced within established ethical boundaries, the perception of conflict of interest is raised. All physicians and physicians in training should adhere to the AMA Code of Medical Ethics, Opinion 8.061, “Gifts to Physicians from Industry” which can be found under the AMA Code of Medical Ethics at www.ama-assn.org/go/ethicalgifts. Johns Hopkins faculty, staff, employees, students, and trainees must adhere to the more restrictive Johns Hopkins Medicine Policy on Interaction with Industry that can be found on HopkinsMedicine.org by clicking Research > For Our Researchers > Research Affairs Offices > Office of Policy Coordination > Policy on Interaction with Industry or directly through this link http://www.hopkinsmedicine.org/Research/OPC/Policy_Industry_Interaction.

DISCLAIMER STATEMENT

The opinions and recommendations expressed by faculty and other experts whose input is included in this program are their own. This enduring material is produced for educational purposes only. Use of the Johns Hopkins University School of Medicine name implies review of educational format design and approach. Please review the complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings, and adverse effects before administering pharmacologic therapy to patients.

CONFIDENTIALITY DISCLAIMER FOR CME ACTIVITY PARTICIPANTS

I certify that I am participating in a Johns Hopkins University School of Medicine CME activity for accredited training and/or educational purposes. I understand that while I am participating in this capacity, I may be exposed to “protected health information,” as that term is defined and used in Hopkins policies and in the federal HIPAA privacy regulations (the Privacy Regulations). Protected health information is information about a person’s health or treatment that identifies the person. I pledge and agree to use and disclose any of this protected health information only for the training and/or educational purposes of my visit and to keep the information confidential. I agree not to post or discuss this protected health information, including pictures and/or videos on any social medial site (e.g. Facebook, Twitter, etc.), in any electronic messaging program or through any portable electronic device. I understand that I may direct to the Johns Hopkins Privacy Officer any questions I have about my obligations under this Confidentiality Pledge or under any of the Hopkins policies and procedures and applicable laws and regulations related to confidentiality. The contact information is Johns Hopkins Privacy Officer, telephone: 410-735-6509, e-mail: HIPAA@jhmi.edu. “The Office of Continuing Medical Education at The Johns Hopkins University School of Medicine, as provider of this activity, has relayed information with the CME attendees/participants and certifies that the visitor is attending for training, education and/or observation purposes only.” For CME questions, please contact the CME Office (410) 955-2959 or e-mail cmenet@jhmi.edu. For certificates, please call (410) 502-9636. Johns Hopkins University School of Medicine Office of Continuing Medical Education Turner 20/720 Rutland Avenue Baltimore, Maryland 21205-2195

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES

As a provider approved by the Accreditation Council for Continuing Medical Education (ACCME), Johns Hopkins University School of Medicine Office of Continuing Medical Education (OCME) requires attested and signed global disclosure of the existence of all financial interests or relationships with ineligible companies from any individual in a position to control the content of a CME activity sponsored by OCME. The following relationships have been reported for this activity:

Ghassan Abou-Alfa, MD, MBA

Grant or Research Support: Agenus, AstraZeneca, BioNtech, Bristol Myers Squibb, Elicio, Genentech, Inc., Helsinn, Parker Institute, Pertyze, Puma, QED, Servier, Yiviva

Consulting Fees: AbbVie, Alligator, AstraZeneca, Autem, Berry Genomics, BioNtech, Bristol Myers Squibb, Eisai, Inc., Exelixis, Genentech, Inc., Incyte, J-Pharma, Merck and Company, Inc., Merus, Neogene, Novartis AG, Servier, Tango, Tempus, Vector, Yiviva

Nilo Azad, MD

Consulting Fees: Agneus, GlaxoSmithKline, Tempus

Honoraria: Astellas, AstraZeneca, Bristol Myers Squibb, Incyte, RevMed, Taiho Advisor: Mirato, RevMed

Membership on Advisory Committees or Review Panels, Board Membership etc, National Institutes of Health Ownership, including stock or stock option ownership privately held: Cage, Haystack, Irazu

Marina Baretti, MD

Advisor: AstraZeneca, Exelixis, Incyte

Katie Bever, MD

Grant or Research Support: Bristol Myers Squibb, Merck and Company, Inc.

Olaya Brewer-Guiterrez, MBBS does not have any financial relationships or relationships to products or devices with ineligible companies.

Mary-Eve Brown, RD, LDN, CSO does not have any financial relationships or relationships to products or devices with ineligible companies.

Richard Burkhart, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Jennifer Chan, MD

Advisor: Curium, Ipsen, Lantheus, Novartis AG

Grant or Research Support: Lilly, Sanofi Stocks in Publicly Traded Companies: Merck and Company, Inc.

Royalties or Patent Beneficiary: UpToDate

Aman Chauhan, MD

Advisor: Novartis AG

Alia Dadabhai, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Jeremy Davis, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Ana de Jesus Acosta, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Ada Graham, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Aditya Halthore, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Kelvin Hong, MBBCH

Grant or research support: BTG Medical, Merit Medical

Advisor: Boston Scientific Corporation, Varian Medical

Scott Kopetz, MD

Consulting Fees: Agneus, Amgen, AVEO, Bayer Health, Boehringer Ingelheim, Bristol Myers Squibb-Medarex, Carina Biotech, Flame Biosciences, Frontier Medicines, Genentech, Harbringer Oncology, Kestrel Therapeutics, Lutris, Merck, Mirati, Pfizer, Replimune, Regeneron, Roche, Revolution Medicines, Tachyon Therapeutics, Tempus, Zentalis

Grant or Research Support: Amgen, Boehringer Ingelheim, BridgeBio, Cardiff, Daiichi Sankyo, EMD Serono, Genentech, Guardant Health, Jazz, Lilly, Medimmune, Mirati, Novartis, Pfizer, Sanofi, Zentalis

Ownership, including stock or stock option ownership privately held: Frontier Medicines, Lutris, Navire

Kelly Lafaro, MD, MPH does not have any financial relationships or relationships to products or devices with ineligible companies.

Rachit Kumar, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Valerie Lee, MD

Advisor: Sirtex Advisory Board: Incyte Grant or Research Support: Merck and Company, Inc.

Robert Liddell, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Saowanee Ngamruengphong, MD

Consulting Fees: Boston Scientific Corporation, Fujifilm, Neptune Medical, Olympus America

Amol Narang, MD Grant or Research Support: Boston Scientific Corporation, Flavocure, Nanocan

Eileen O'Reilly, MD

Grant or Research Support: AbbVie, Agenus, Arcus, AstraZeneca, Atara, Beigene, Genentech Roche, Helsing, Parker Institute, Pertyze, Yiviva

Consulting Fees: AbbVie, Ability Pharma, Agenus, Alligator Biosciences, Astellas, Berry Genomics, BioNTech, Boehringer Ingelheim, Bristol Myers Squibb, Genentech, Ipsen, J Pharma, Merck, Merus, Moma, Neogene, Novartis, Regeneron, Revolution Medicines, Servier

Michael Pishvaian, MD, PhD

Consulting Fees: AstraZeneca, Merck and Company, Inc., Merus, Moderna, RenovoRx, Seattle Genetics

Ownership, including stock or stock option ownership privately held: Perthera, Serna Bio

Other relevant financial or material interests: Astellas Honoraria: Pfizer, Inc., Novartis AG

Membership on Advisory Committees or Interview Panels, Board Membership, etc.: Astellas, Trisalus

Grant or Research Support: Actutate, Amgen, Astellas, Arcus Bio, Biomed Valley Discoveries, Boehringer Ingelheim, Elevation Oncology, Hutchinson Medipharma, Ideaya, MEI Pharma, Merck and Company, Inc., Novartis AG, Pfizer, Inc., Recursion Pharma, RenovoRx, Repare, Seattle Genetics, Takeda Pharmaceuticals, Inc., Tesaro, Tizoni

Flavio Rocha, MD

Advisor: BetaGlue

Consulting Fee: AstraZeneca

Manish Shah, MD does not have any financial relationships or relationships to products or devices with ineligible companies.

Cynthia Shephard, MSN, RN, CWOCN does not have any financial relationships or relationships to products or devices with ineligible companies.

Rachna Shroff, MD

Advisor: Astellas, AstraZeneca, Boehringer Ingelheim Vetmedica GmbH, Clovis, Duo Oncology, Elevar Therapeutics, Genentech, Inc., Incyte, Merck and Company, Inc., Natera, QED Therapeutics, Servier, Taiho, Zymeworks Biopharm

Grant or Research Support: Bayer Corporation, Bristol Myers Squibb Aventis, Exelixis Pharm., IMV Inc., LOXO, Novocure, NUCANA, Pieris, Rafael Pharm., Seagen

Consulting Fees: AbbVie, Hookipa Pharm., SYROS Independent Contractor: Ability Pharm.

Keith Unger, MD

Honoraria: Mevion Medical Systems

Mark Yarchoan, MD

Consulting Fees: AstraZeneca, Eisai, Inc., Exelixis, Genentech, Inc., Hepion, Lantheus, Replimune

Grant or Research Support: Bristol Myers Squibb, Exelixis, Genentech, Inc., Incyte

Neeha Zaidi, MD

Consulting Fees: Adventris Pharmaceuticals, Genentech, Inc.

Grant or Research Support: Adventris Pharmaceuticals, Bristol Myers Squibb

No one else in a position to control the content of this educational activity has disclosed a relevant financial interest or relationship with ineligible companies. All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

ACKNOWLEDGEMENT

We wish to acknowledge the following company that has provided or pledged an educational grant in support of this activity. Please note that commercial support received is solely for the educational component of the activity.

Exelixis
Ipsen
Novartis Pharmaceuticals Corporation

LIST FACULTY NAMES/CREDENTIALS/AFFILIATIONS

Ghassan Abou-Alfa, MD, MBA

Professor

Memorial Sloan Kettering Cancer Center

New York, New York

Nilo Azad, MD

Co-Director, Cancer Genetics and Epigenetics

Professor of Oncology

Johns Hopkins University School of Medicine

Baltimore, Maryland

Marina Baretti, MD

Assistant Professor of Oncology

Jiasheng Professorship in Hepato-Biliary Cancer Research

Johns Hopkins University School of Medicine

Baltimore, Maryland

Katie Bever, MD

Associate Professor of Oncology

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Olaya Brewer-Gutierrez, MBBS

Director of Endoscopy

Sibley Memorial Hospital

Assistant Professor of Medicine

Johns Hopkins University School of Medicine

Baltimore, Maryland

Mary-Eve Brown, RD, LDN, CSO

Dietician

Johns Hopkins Center for Stomach Cancer Care

Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland

Richard Burkhart, MD

Assistant Professor of Surgery

Johns Hopkins Hospital

Baltimore, Maryland

Jennifer Chan, MD

Institute Physician, Department of Medical Oncology

Dana-Farber Cancer Institute

Associate Professor of Medicine

Harvard Medical School

Boston, Massachusetts

Aman Chauhan, MD

Leader, Neuroendocrine Tumor Program

Co-Director, Theragnostic Program

University of Miami

Miami, Florida

Alia Dadabhai, MD

Assistant Professor of Medicine

Johns Hopkins University School of Medicine

Baltimore, Maryland

Jeremy Davis, MD

Chief, Division of Surgical Oncology

University of Maryland Medical System

Baltimore, Maryland

Ana de Jesus Acosta, MD

Associate Professor of Oncology

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Ada Graham, MD

Assistant Professor of Surgery

Johns Hopkins University School of Medicine

Baltimore, Maryland

Aditya Halthore, MD

Assistant Professor

Department of Radiation Oncology and Molecular Radiation Sciences

Johns Hopkins University School of Medicine

Baltimore, Maryland

Kelvin Hong, MBBCH

Executive Vice Chair, Radiology

Associate Professor of Radiology and Radiological Science

Johns Hopkins Medicine

Baltimore, Maryland

Scott Kopetz, MD

Deputy Chair, Translational Research

Department of Gastrointestinal Medical Oncology

University of Texas MD Anderson Cancer Center

Houston, Texas

Kelly Lafaro, MD, MPH

Assistant Professor of Surgery

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Rachit Kumar, MD

Assistant Professor, Radiation Oncology and Molecular Radiation Sciences

Johns Hopkins University School of Medicine

Baltimore, Maryland

Valerie Lee, MD

Instructor, Medical Oncology

Johns Hopkins University School of Medicine

Associate Professor of Oncology

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Bud Liddell, MD

Associate Professor of Radiology, Surgery and Oncology

Director of Interventional Radiology

Johns Hopkins University School of Medicine

Baltimore, Maryland

Saowanee Ngamruengphong, MD

Associate Professor of Medicine

Associate Director, Gastroenterology & Hepatology Fellowship

Division of Gastroenterology & Hepatology.

Johns Hopkins Medicine

Baltimore, Maryland

Amol Narang, MD

Associate Professor

Johns Hopkins Department of Radiation Oncology & Molecular Sciences

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Eileen O'Reilly, MD

Winthrop Rockefeller Endowed Chair

Medical Oncology

Memorial Sloan Kettering

New York, New York

Michael Pishvaian, MD, PhD

Director, Gastrointestinal, Developmental Therapeutics and Clinical Research Programs

Associate Professor of Oncology

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

Flavio Rocha, MD

Professor and Division Head

Division of Surgical Oncology

Oregon Health & Science University

Portland, Oregon

Manish Shah, MD

Director, Gastrointestinal Oncology Program

Weill Cornell Medicine

New York, New York

Cynthia Shephard, MSN, RN, CWOCN

Nurse Coordinator, Ambulatory Wound Ostomy Nurse Service

Johns Hopkins Bayview Medical Center

Baltimore, Maryland

Rachna Shroff, MD

Associate Director, Clinical Investigations

Professor, Department of Medicine

University of Arizona Cancer Center

Tucson, Arizona

Keith Unger, MD

Physician Executive Director

Radiation Oncology Service Line

MedStar Health

Washington, District of Columbia

Mark Yarchoan, MD

Associate Professor, Division of Gastrointestinal Malignancies

Sidney Kimmel Comprehensive Cancer Center

Johns Hopkins

Baltimore, Maryland

Neeha Zaidi, MD

Associate Professor of Oncology

Johns Hopkins Kimmel Cancer Center

Baltimore, Maryland

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Claim Credit

TITLE OF ACTIVITY:

PRESENTED BY:

DESCRIPTION

WHO SHOULD PARTICIPATE

OBJECTIVES

ACCREDITATION STATEMENT

CREDIT DESIGNATION STATEMENT

POLICY ON PRESENTER AND PROVIDER DISCLOSURE

NOTICE ABOUT OFF-LABEL USE PRESENTATIONS

JOHNS HOPKINS STATEMENT OF RESPONSIBILITY

COPYRIGHT

COURSE FORMAT – METHOD OF PARTICIPATION

HOW TO OBTAIN CME CREDIT

PREREQUISITES FOR PARTICIPANTS

HARDWARE/SOFTWARE REQUIREMENTS

POST-TEST

RELEASE DATE

EXPIRATION DATE

WHAT YOU SHOULD KNOW ABOUT GIFTS TO PHYSICIANS FROM INDUSTRY

DISCLAIMER STATEMENT

CONFIDENTIALITY DISCLAIMER FOR CME ACTIVITY PARTICIPANTS

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES

ACKNOWLEDGEMENT

LIST FACULTY NAMES/CREDENTIALS/AFFILIATIONS